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The efficiency of pre-mixed herbicide of Dicamba + Prosulfuron (Casper®, 55% WG) in four regions of Karaj, Shiraz, Dezful and Mashhad in 2019-2020 was studied in a randomized complete block design with four replications. Treatments, Casper in the amounts of 300, 400 and 500 g/ha alone and mixture with nonionic surfactants (Adigor and Citogate), bromoxynil + MCPA (bromycid MA® 40% EC) with a rate of 1.5 l / ha, Tria sulfurone + Dicamba (Lentur® WG 70%) at 165 g/ha, Bentazone + Dicloprop (bazagran DP® 56.6% SL) at 2 l / ha and Bromoxynil + 2,4-D (Buctryl Universal® EC 56%) at 1.25 l / ha was sprayed at Wheat tillering stage.. Application of Casper herbicide in all amounts used alone and mixture with nonionic surfactants (Adigor and Citogate were effective and reduced the dry weight of the dominant weeds in Karaj (75 up to 100%), Shiraz (85 up to 93%), Dezful (70 up to 100%) and Mashhad (42 up to 97%). According to the ocular estimation (EWRC), Casper herbicide was effective in controlling of dominant broadleaf weeds in Karaj (78-94% control), Shiraz (88-94% control) and Dezful (94-98% control). In general, based on the results of the evaluated traits, the difference in efficiency of Casper herbicide in the amount of 300 to 500 g/ha with comparative herbicides was inconsiderable in most regions. Thus, use of Casper herbicide at the rate of 300 g / ha with citogate (1.5 l / ha) is recommended to control of broadleaf weeds in wheat.Key words: Broadleaf weed, Synthetic auxin, ALS inhibitor, dry weight, yield
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