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This study was carried out to identify high yielding lines/cultivars in comparison to the commercial cultivars. Sixty four lines and cultivars including three checks (Mehregan , Barat & Chamran2) were studied in one experiment, in four experimental field stations (Dezful, with full irrigation and Darab, Ahwaz and Zabol with reduced irrigation) in southern dry and warm zone, using Alpha-Lattice design with two replications. These new lines were selected from the preliminary regional yield trials (PRWYT-Z2) of 2017–2018 cropping season. The new lines were compared with CVs. Mehregan, Barat & Chamran2, regarding grain yield, agronomic performance, adaptability as well as reaction to major diseases in the target areas. These lines were also studied for their reaction to major diseases in knowing the hot spots for Yellow Rust (YR), Leaf Rust (LR), Septorios etc. in special diseases nurseries, under natural and artificial inoculating conditions. Yield potential, desired agronomic characteristics and reaction to major diseases were considered as the main criteria in the final evaluation and selection. Statistics such as mean grain yield, mean rank (R), standard deviation of rank (SDR), and agronomic characteristics were used in the selection of superior lines. Selected lines had a higher grain yield, low R & SDR, and desired agronomic characteristic: flowering time, plant height (90–95cm), tolerance /resistance to major diseases, suitable physiological maturity period, desired grain color (Amber is preferred). Nineteen lines based on the above criteria were selected to be studied in the Elite Regional Uniform yield trials (ERWYT) in southern warm and dry zone in the 2019 –21 cropping season.Key Words: Advanced lines, Grain yield, adaptability, bread wheat
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